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Immunobiology, Part 3
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    I’ll say it now: if you haven’t read Part 1 or Part 2 in my Immunobiology series -- what are you doing just trying to jump in like this? -- check it out here. Nothing against you, but you can’t do that. I understand that the big word in the title makes you want to look, but unfortunately you can’t jump in and learn without background knowledge. If you have that, then welcome! And now that the lazy people are gone, let’s dive into the sideline fighters of the Immune System.

    The immune system is crucial to your body’s survival. And in previous chapters we discussed the T cells and the basic fighters. You know that we can’t survive without  them, so let’s talk about something else: the fighters that … Don’t fight? 

The chemical buildup of Histamine

 Mastizillen -- German, for “Fattening” -- this is the word scientists used to name the Mast cell. The mast cell is a cell that releases a chemical called Histamines when they detect a harmful substance. Don’t you hate when your nose is stuffed because of all that mucous and you can’t breathe? It’s not. It’s actually the nose being inflamed due to the release of histamine in the nasal cavities. You see, histamine is a chemical that kills things, yes, but also dilates blood vessels. Think of it as a balloon that expands to widen the blood vessel. The dilation of blood vessels allows for immune cells to rush to the scene and fight off whatever is attacking.

    Do you remember how the Killer T cells require activation before they can fight, or need to know what they are fighting? That is where APC (Antigen presenting cells) come into play. The Dendritic cell is one of these cells. APC Cells present antigens (Viruses or bacteria/ allergens) to Helper T cells in order to allow them to deploy the Killer T cells. Dendritic Cells are also able to release cytokines, stimulating an immune response.


    Sorry for the short chapter: I couldn’t find enough information to make it longer. Still, thank you for tuning in to my Immunobiology series! And with that, Have a marvelous day.


    And now, as Tanjiro would say, it’s time for a "Taisho Era secret": I may begin recording a weekly podcast talking about (and answering) common Immunobiology questions. But don’t tell anyone!

Reporting by Garrett J; Editing by Garret J. and Mr. Flesher

    
Images used according to the creative commons license.
Dendritic cell diagram
Mast cell diagram
Histamine Chemical build 
 

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